Glucosamine stimulates cartilage production and repair, addressing joint wear and tear. The consumption of this substance is likely to increase the production level of hyaluronic acid in the joints. Sodium Chondroitin Sulfate, a natural substance in the body, safeguards cartilage from enzymatic damage, promoting pain relief and potential cartilage repair. Avocado/Soybean Unsaponifiables (ASU), made from avocado fruits and seeds and soybean oil, offer potent anti-inflammatory effects. ASU is an adjunctive treatment for arthritic pain relief and slow-acting symptomatic treatment of hip and knee osteoarthritis. Green tea extract, rich in polyphenols, acts as a potent anti-inflammatory agent in pain relief products. Ongoing studies highlight the potential of Boswellia serrata extract as an adjunctive treatment for knee pain and osteoarthritis